Publications

Caputo DR, Robson SC, Werner I, Ford A (2020). Complete transcriptome assembly and annotation of a critically important amphipod species in freshwater ecotoxicological risk assessment - gammarus fossarum. Environment International, 137, 105319.

Lerebours A, Robson S, Sharpe C, Smith J (2020). Subtle effects of radiation on embryo development of the 3-spined stickleback. Chemosphere 126005.

Young C, Gosselin MRF, Rumney RMH, Oksiejuk A, Chira N, Bozycki L, Matryba P, Łukasiewicz K, Kao A, Dunlop JN, Robson SC, Zabłocki K, Gorecki D (2019). Total absence of dystrophin expression exacerbates ectopic myofiber calcification and fibrosis and alters macrophage infiltration patterns. American Journal of Pathology, 190 (1), p190-205.

Samudyata, Amaral, PP, Engström, PG, Sam Robson, Nielsen, ML, Kouzarides, T, Castelo-Branco, G (2019). Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells. Experimental Cell Research, Vol. 381, No. 1, 01.08.2019, p. 129-138..

Pandolfini, L, Barbieri, I, Bannister, AJ, Hendrick, A, Andrews, B, Webster, N, Murat, P, Mach, P, Brandi, R, Sam Robson, Migliori, V, Alendar, A, D’Onofrio, M, Balasubramanian, S, Kouzarides, T (2019). METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Molecular Cell, Vol. 74, 20.06.2019, p. 1-13.

Róg, J, Oksiejuk, A, Gosselin, MRF, Brutkowski, W, Dymkowska, D, Nowak, N, Sam Robson, Górecki, DC, Zabłocki, K (2019). Dystrophic mdx mouse myoblasts exhibit elevated ATP/UTP-evoked metabotropic purinergic responses and alterations in calcium signalling. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 24.01.2019.

Tzelepis, K, De Braekeleer, E, Aspris, D, Barbieri, I, Vijayabaskar, MS, Liu, W, Gozdecka, M, Metzakopian, E, Toop, HD, Dudek, M, Sam Robson, Hermida-Prado, F, Yang, YH, Babaei-Jadidi, R, Garyfallos, DA, Ponstingl, H, Dias, JML, Gallipoli, P, Seiler, M, Buonamici, S, Vick, B, Bannister, AJ, Rad, R, Prinjha, RK, Marioni, JC, Huntly, B, Batson, J, Morris, JC, Pina, C, Bradley, A, Jeremias, I, Bates, DO, Yusa, K, Kouzarides, T, Vassiliou, GS (2018). SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4. Nature Communications, Vol. 9, No. 1, 5378, 19.12.2018.

Millan-Zambrano G, Santos-Rosa H, Puddu F, Sam Robson, Jackson S, Kouzarides T (2018). Phosphorylation of histone H4T80 triggers DNA damage checkpoint recovery. Molecular Cell, Vol. 72, No. 4, 15.11.2018, p. 625-635.e4.

Larrieu D, Virè E, Sam Robson, Breusegem S, Kouzarides T, Jackson S (2018). Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway. Science Signaling 03 Jul 2018: Vol. 11, Issue 537, eaar5401.

Barbieri I, Tzelepis K, Pandolfini L, Shi J, Millán-Zambrano G, Sam Robson, Aspris D, Migliori V, Bannister AJ, Han N, De Braekeleer E, Ponstingl H, Hendrick A, Vakoc CR, Vassiliou GS, Kouzarides T (2017). Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control. Nature 2017 December; 552: 126-131.

Li M, Amaral P, Cheung P, Bergmann J, Kinoshita M, Kalkan T, Ralser M, Sam Robson, Meyenn F, Paramor M, Yang F, Chen C, Nichols J, Spector D, Kouzarides T, He L, Smith A (2017). A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation. eLife. 2017 Aug 18;6. pii: e23468.

Sayou C, Millán-Zambrano G, Santos-Rosa H, Petfalski E, Sam Robson, Houseley J, Kouzarides T, Tollervey D (2017). RNA binding by the histone methyltransferases Set1 and Set2. Mol. Cell. Biol. 2017 July;37(14):e00165-17.

Bamborough P, Chung CW, Demont EH, Furze RC, Bannister AJ, Che KH, Diallo H, Douault C, Grandi P, Kouzarides T, Michon AM, Mitchell DJ, Prinjha RK, Rau C, Sam Robson, Sheppard RJ, Upton R, Watson RJ (2016). A Chemical Probe for the ATAD2 Bromodomain. Angew Chem. Int. Ed. Engl. 2016 Sep 12;55(38):11382-6.

Picaud S, Fedorov O, Thanasopoulou A, Leonards K, Jones K, Meier J, Olzscha H, Monteiro O, Martin S, Philpott M, Tumber A, Filippakopoulos P, Yapp C, Wells C, Che K, Bannister A, Sam Robson, Kumar U, Parr N, Lee K, Lugo D, Jeffrey P, Taylor S, Vecellio M, Bountra C, Brennan P, O’Mahony A, Velichko S, Müller S, Hay D, Daniels D, Urh M, La Thangue N, Kouzarides T, Prinjha R, Schwaller J, Knapp S (2015). Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy. Cancer Res. 2015 Dec 1;75(23):5106-5119.

Viré E, Curtis C, Davalos V, Git A, Sam Robson, Villanueva A, Vidal A, Barbieri I, Aparicio S, Esteller M, Caldas C, Kouzarides T (2014). The breast cancer oncogene EMSY represses transcription of antimetastatic microRNA miR-31. Mol Cell. 2014 Mar 6;53(5):806-18.

Dawson M, Gudgin E, Horton S, Giotopoulos G, Meduri E, Sam Robson, Cannizzero E, Osaki H, Wiese M, Putwain S, Fong C, Grove C, Craig J, Dittmann A, Lugo D, Jeffrey P, Drewes G, Lee K, Bullinger L, Prinjha R, Kouzarides T, Vassiliou G, Huntly P (2014). Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia. Leukemia. 2014 Feb;28(2):311-20.

Tessarz P, Santos-Rosa H, Sam Robson, Sylvestersen K, Nielson C, Kouzarides T (2014). Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification. Nature. 2014 Jan 23;505(7484):564-8.

Wyspianska B, Bannister A, Barbieri I, Nangalia J, Godfrey A, Calero-Nieto F, Sam Robson, Rioja I, Li J, Wiese M, Cannizzaro E, Dawson M, Huntly B, Prinjha R, Green A, Gottgens B, Kouzarides T (2014). BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms. Leukemia. 2014 Jan;28(1):88-97.

Castelo-Branco G, Amaral P, Engström P, Sam Robson, Marques S, Bertone P, Kouzarides T (2013). The non-coding snRNA 7SK controls transcriptional termination, poising, and bidirectionality in embryonic stem cells. Genome Biology 2013 Sep 17;14(9):R98.

Xhemalce B, Sam Robson, Kouzarides T (2012). Human RNA methyltransferase BCDIN3D regulates microRNA processing. Cell. 2012 Oct 12; 151(2): 278–288.

Dawson M, Foster S, Bannister A, Sam Robson, Hannah R, Wang X, Vhemalce B, Wood A, Green A, Göttgens B, Kouzarides T (2012). Three distinct patterns of histone H3Y41 phosphorylation mark active genes. Cell Rep. 2012 Sep 27;2(3):470-7.

Sam Robson, Ward L, Brown H, Turner H, Hunter E, Pelengaris S, Khan M (2011). Deciphering c-MYC-regulated genes in two distinct tissues. BMC Genomics. 2011 Sep 30;12:476.

Dawson MA, Prinjha RK, Dittmann A, Giotopoulos G, Bantscheff M, Chan WI, Sam Robson, Chung CW, Hopf C, Savitski MM, Huthmacher C, Gudgin E, Lugo D, Beinke S, Chapman TD, Roberts EJ, Soden PE, Auger KR, Mirguet O, Doehner K, Delwel R, Burnett AK, Jeffrey P, Drewes G, Lee K, Huntly BJ, Kouzarides T (2011). Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia. Nature. 2011 Oct 2;478(7370):529-33.

Bartke T, Vermeulen M, Xhemalce B, Sam Robson, Kouzarides T (2010). Nucleosome-interacting proteins regulated by DNA and histone methylation. Cell 2010 Oct 29;143(3):470-84.

Conrad D, Pinto D, Redon R, Feuk L, Gokcumen O, Zhang Y, Aerts J, Andrews D, Barnes C, Campbell P, Fitzgerald T, Hu M, Hwa C, Kristiansson K, Macarthur D, Macdonald J, Onyiah N, Wing Chun Pang A, Sam Robson, Stirrups K, Valsesia A, Walter K, Wei J, Tyler-Smith C, Carter N, Lee C, Scherer S, Hurles M (2010). Origins and functional impact of copy number variation in the human genome. Nature 2010 Apr 1;464(7289):704-12.

Wellcome Trust Case Control Consortium, Craddock N, Hurles ME, Cardin N, Pearson RD, Plagnol V, Sam Robson, Vukcevic D, Barnes C, Conrad DF, Giannoulatou E, Holmes C, Marchini JL, Stirrups K, Tobin MD, Wain LV, Yau C, Aerts J, Ahmad T, Andrews TD, Arbury H, Attwood A, Auton A, Ball SG, Balmforth AJ, Barrett JC, Barroso I, Barton A, Bennett AJ, Bhaskar S, Blaszczyk K, Bowes J, Brand OJ, Braund PS, Bredin F, Breen G, Brown MJ, Bruce IN, Bull J, Burren OS, Burton J, Byrnes J, Caesar S, Clee CM, Coffey AJ, Connell JM, Cooper JD, Dominiczak AF, Downes K, Drummond HE, Dudakia D, Dunham A, Ebbs B, Eccles D, Edkins S, Edwards C, Elliot A, Emery P, Evans DM, Evans G, Eyre S, Farmer A, Ferrier IN, Feuk L, Fitzgerald T, Flynn E, Forbes A, Forty L, Franklyn JA, Freathy RM, Gibbs P, Gilbert P, Gokumen O, Gordon-Smith K, Gray E, Green E, Groves CJ, Grozeva D, Gwilliam R, Hall A, Hammond N, Hardy M, Harrison P, Hassanali N, Hebaishi H, Hines S, Hinks A, Hitman GA, Hocking L, Howard E, Howard P, Howson JM, Hughes D, Hunt S, Isaacs JD, Jain M, Jewell DP, Johnson T, Jolley JD, Jones IR, Jones LA, Kirov G, Langford CF, Lango-Allen H, Lathrop GM, Lee J, Lee KL, Lees C, Lewis K, Lindgren CM, Maisuria-Armer M, Maller J, Mansfield J, Martin P, Massey DC, McArdle WL, McGuffin P, McLay KE, Mentzer A, Mimmack ML, Morgan AE, Morris AP, Mowat C, Myers S, Newman W, Nimmo ER, O’Donovan MC, Onipinla A, Onyiah I, Ovington NR, Owen MJ, Palin K, Parnell K, Pernet D, Perry JR, Phillips A, Pinto D, Prescott NJ, Prokopenko I, Quail MA, Rafelt S, Rayner NW, Redon R, Reid DM, Renwick, Ring SM, Robertson N, Russell E, St Clair D, Sambrook JG, Sanderson JD, Schuilenburg H, Scott CE, Scott R, Seal S, Shaw-Hawkins S, Shields BM, Simmonds MJ, Smyth DJ, Somaskantharajah E, Spanova K, Steer S, Stephens J, Stevens HE, Stone MA, Su Z, Symmons DP, Thompson JR, Thomson W, Travers ME, Turnbull C, Valsesia A, Walker M, Walker NM, Wallace C, Warren-Perry M, Watkins NA, Webster J, Weedon MN, Wilson AG, Woodburn M, Wordsworth BP, Young AH, Zeggini E, Carter NP, Frayling TM, Lee C, McVean G, Munroe PB, Palotie A, Sawcer SJ, Scherer SW, Strachan DP, Tyler-Smith C, Brown MA, Burton PR, Caulfield MJ, Compston A, Farrall M, Gough SC, Hall AS, Hattersley AT, Hill AV, Mathew CG, Pembrey M, Satsangi J, Stratton MR, Worthington J, Deloukas P, Duncanson A, Kwiatkowski DP, McCarthy MI, Ouwehand W, Parkes M, Rahman N, Todd JA, Samani NJ, Donnelly P (2010). Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature. 2010 Apr 1;464(7289):713-20.